Circe is the daughter of Helios and Perseis. She is not very liked in her family and mother, father, brothers, sisters, uncles and aunts tended to mock her easily, making her life difficult. On day, she discover her power by transforming a fisherman into a god. She continues by transforming the mean Nymph Scylla into a monster.
When Helios learns that all the children of Perseis have the witchcraft power, he makes a deal with Zeus, protecting all 3 of them and sacrificing Circe by exiling her into an Island. There, she improves her skill and eventually meet Odysseus, with which she will get her son Telegonus. But Athena, having heard of a tale, tries to claim and kill Telegonus. Circe is then focused on protecting him by keeping him safe on the island, despite his desire to discover the world. Eventually, she will have to accept that he leaves to meet his father.
When Telegonus reach Ithaca and meet his father, Odysseus is sour and angry and try to kill him. Protected by the spear made of the tail of Trigon that Circe got for him, he scratches his father by accident, letting the poison go through and kill him instantly. He comes back to his mother with his half brother Telemachus and her mother Penelope.
Athena, having lost her protege Odysseus, comes to claim his son Telemachus, who refuses. Instead she takes Telegonus who sees an opportunity to discover the world and get a kingdom.
Circe will eventually bond romantically with Telemachus. Strong with her new confidence and powers, she confronts her father and forces him to lift the exile. She offers the island to Penelope and leave with Telemachus for her last fight with Scylla where she transforms her to rock.